Research ArticleBIOMIMETICS

An organosynthetic dynamic heart model with enhanced biomimicry guided by cardiac diffusion tensor imaging

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Science Robotics  29 Jan 2020:
Vol. 5, Issue 38, eaay9106
DOI: 10.1126/scirobotics.aay9106

Article Information

vol. 5 no. 38

Published By: 
History: 
  • Received July 29, 2019
  • Accepted January 8, 2020
  • .

Author Information

  1. Clara Park1,
  2. Yiling Fan1,2,
  3. Gregor Hager3,4,
  4. Hyunwoo Yuk1,
  5. Manisha Singh3,5,
  6. Allison Rojas3,
  7. Aamir Hameed6,7,
  8. Mossab Saeed2,8,
  9. Nikolay V. Vasilyev2,8,
  10. Terry W. J. Steele5,9,
  11. Xuanhe Zhao1,10,
  12. Christopher T. Nguyen2,11,12,*, and
  13. Ellen T. Roche1,2,3,*,
  1. 1Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  2. 2Harvard Medical School, Boston, MA, USA.
  3. 3Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA.
  4. 4Department of Mechanical Engineering, Technical University of Munich, Munich, Germany.
  5. 5NTU-Northwestern Institute for Nanomedicine, Interdisciplinary Graduate School, Nanyang Technological University, Singapore, Singapore.
  6. 6Tissue Engineering Research Group, Department of Anatomy, Royal College of Surgeons in Ireland, Dublin, Ireland.
  7. 7Trinity Centre for Biomedical Engineering, Trinity College Dublin, Dublin, Ireland.
  8. 8Department of Cardiac Surgery, Boston Children’s Hospital, Boston, MA, USA.
  9. 9School of Materials Science and Engineering, Nanyang Technological University, Singapore, Singapore.
  10. 10Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  11. 11Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.
  12. 12Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA, USA.
  1. Corresponding author. Email: christopher.nguyen{at}mgh.harvard.edu (C.T.N.); etr{at}mit.edu (E.T.R.)
  1. * These authors contributed equally to this work.

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