24 April 2019
Vol 4, Issue 29

About The Cover

Cover image expansion

ONLINE COVER A DASH of Bioengineering. A defining feature of living organisms is the ability to use environmental molecules for growth, movement, and other dynamic processes. Hamada et al. made precursor DNA that, when added to a microfluidic device containing pre-patterned boundaries and obstacles, could assemble into polymers, then micrometer-scale hydrogels and last mesoscale patterns and shapes. The DASH (DNA-based Assembly and Synthesis of Hierarchical) materials could be generated and degenerated autonomously and synchronously, allowing further programming to enable locomotion similar to slime mold movement and even "racing" of side-by-side formations. [CREDIT: SHOGO HAMADA/CORNELL UNIVERSITY]